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This is a list of fictional medicines and drugs from works of fiction (usually fantasy or science fiction). Some of the items listed as medicines or drugs, may be used as both or in other capacities, but fictional works are often vague on such distinctions. Grouping is done by what seems most likely.

Fictional medicines

These drugs and vaccines are meant primarily for medicinal and analgesic use, though they can possibly be abused.

Performance and lifestyle enhancers

These drugs are for enhancing strength, intelligence, and other attributes. Steroids, birth control pills, and antidepressants fall into this category.

Recreational

Drugs used for narcotic, hallucinogenic or other recreational usage. These drugs tend to be illegal and addictive, sometimes dangerously so.

Other/unspecified

Snake oils can be found here. Also for compounds whose properties are not known.

To be added

• * Adneman - Desperate Housewives - A fictional painkiller that was used by Mike Delfino to relive his pain after car accident (S04E07 - You Can't Judge a Book by Its Cover)
• Adrenochrome - not to be confused real chemical of the same name, supposedly taken directly from the adrenaline gland of a living human being, used in the 1999 film Fear and Loathing in Las Vegas and taken directly from Hunter Thompson's text original.
• Anaproviline - Star Trek
• Aphrodite - Get Backers - A white powder which was from the Venus De Milo storyline. It is highly expensive and addictive and can be taken via needle although it is unclear as to whether it is administered subcutaineously, intramuscularly, or via IV. Its effects are severely dibilitating, and on one character induces paranoia, catatonia, and loss of the ability to walk. Apparently rare even within the Limitless Fortress. Hardened and compacted, Aphrodite was fashioned into a fake Venus.
• Backlash - Blackcollar - A drug taken to greatly improve the speed and reflexes of elite commandos known as the Blackcollar during the war between humans and an alien race called Ryqril. Together with Idunine for health and geriatic effects, an RNA derivative to speed up learning, and the very best psychological and anti-interrogation training, it created more effective warriors than anything known in previous human history. During and after the war the Backlash drug was mostly destroyed by the alien victors, who didn't want more Blackcollars being trained in secret, though it is hoped that instructions on how to make the drug still exist. Little is known about the drug itself.
• Blue Dreamers - Saturn 3
• Blue Pill - EVE Online
• BTL - "Beetle" (Better Than Life) electronic drug not unlike Tek from the Shadowrun roleplaying game.
• Butazamine - Dead Ringers - Diet pill (Amphetamine). Claire Niveau uses it as an aphrodisiac.
• Fly - military drug which increases strength, speed and stamina. Soldiers of Anarchy
• Flora-Flor - A fictitious over-the-counter drug created by comedian Jeff Foxworthy. Is used to treat "itchy, watery eyes" but has 50 negative side-effects, from "back pain" to "low resale value on your home". (Add to list when you learn all 50).
• Calminex - South Park mentioned in South Park episode "Quest for Ratings". Cough medicine. Possibly a reference to Dextromethorphan. Also mentioned in Jonathan Coulton's song "I Feel Fantastic".
• Cat Urine - South Park - In the episode Major Boobage cat urine serves an hallucinogen that when is inhaled it would make the person look like he is in another world filled with breasts(parodying the film Heavy Metal) in which they are allowed to have sex with king's daughter.
• chlorhexinol - The Simpsons
• Clarity - Minority Report (This is the street name for Neuroin)
• Coldkiller X - Phoenix Wright
• Comatonin - Futurama
• Cortitussin Cough and Cold- South Park makes you "trip balls", mentioned in South Park episode "Quest for Ratings". Cough medicine.
• Crash - EVE Online
• Crystal Dream - Harley Davidson and the Marlboro Man
• Crystal Egg - EVE Online
• cyclobenzanone - The Simpsons
• Dancer - All Tomorrow's Parties by William Gibson
• Daytab Cold and Flu- South Park causes a "lucid, speedy kind of high", mentioned in South Park episode "Quest for Ratings". Cough medicine.
• Desperance - Forward the Foundation . See also: Raych Seldon
• Deverol - Law & Order Synthetic narcotic with effects similar to Pethidine (Demerol). Causes fatal drug interations with MAOI antidepressants
• dexatrimfan - South Park active ingredient in Calminex PM, cough medicine that "causes hallucinations in large doses".
• Dragon's Milk/Peca Various Bordertown books Used only by Truebloods (elves), it doesn't produce a high in humans, although it does cause severe nausea and vomiting. While the specific effects are uncertain, the initial rush feels like the top of your head gets blown off (but in a good way?) and you only remember pieces of what happens while you're on it. You can drink it, or smear a concentrated form on open cuts, usually made on the wrists or arms.
• Drop - EVE Online
• Drug Bug - Let's visit the World of the Future (By Ivan Stang). a highly contagious artificially created disease that causes extreme euphoria and a state of mild delirium in those infected by it.
• Exile - EVE Online
• Eye Candy - Command & Conquer: Tiberian Sun. A drug taken in form of eye drops. Effects similar to cocaine.
• E-Z 4 - "Close Encounters of the Third Kind". An aerosol sleep-inducing agent. Non-fatal and fast-acting, but causes a bad headache.
• Fairy dust various books in the Bordertown series Both a cosmetic and a recreational drug, and the refined for of a substance by the same name used to make graffiti sparkle. Not very chemically addictive, but causes powerful psychological dependence in humans (although not in elves). Addicts are called "dust heads" and can be identified by the glittery aura around them, as well as by the fact that they walk into walls. Apparently hallucinogenic, users 'babble about faeries'. Cosmetically worn on the skin, or in hair, where it looks like glitter, and gives the faces of human wearers a 'vaguely elven' appearance. It can be snorted to get high, and whether it will get you high when used as makeup is debatable.
• Flash- "The Warriors (Video Game)"
• Frentix - EVE Online
• Glint (aka Devil's Hairlip) - Strangers with Candy
• Glycolauric Octanol (AKA "Glow") - Final Fight: Streetwise
• Goblin Fruit the essential bordertown: a travelers guide to the edge of faerie Fruit that looks like small gold plums. Mildly hallucinogenic, and non addictive.
• Golden - The Sentinel (TV series)
• Goofballs - The Simpsons
• Havidol (avafynetyme HCl) - from Havidol website
• Haza - Supernova
• Heatstroke - TKKG Novels Series - a fictional and addictive designer drug
• Hobbitweed - J.R.R. Tolkien's The Lord of the Rings - a mild narcotic, evidently much like marijuana, smoked in pipes.
• Hyoscine-pentothal - A fistional pain-inducing drug used by CTU for interrogation methods on 24.
• Hyperdrene - Alan Moore's Top 10 series -a hallucinogenic club drug; the pixie-like hallucinations it produces in users can be seen and heard by others, to their annoyance.
• Idunine - Blackcollar - essentially a youth drug, it would help a human being maintain their health, muscle and joints in good shape for decades. The availability of idunine, however limited, kept most surviving veterans of the Human-Ryqril war still very capable for duty thirty years later, when the story of the Blackcollar series takes place.
• Iocaine/iocane powder - The Princess Bride - a deadly poison which is odorless and from Australia.
• Iso-36 - Spider-Man - The serum developed by Dr. Curt Connors to cure radiation poisoning.
• Juvenat - Warhammer 40,000 - Designed to retard the aging process in humans, it can allow someone who has regular treatment (normally nobility, Imperial Guard officers or Inquisitors) to live for several centuries.
• Kamyla - sex drug, which suppresses free will. Kamyla.
• Key 17 and Key 23 - The Invisibles
• KT-28 - Watchmen
• MA-19 - Michael Moorcock's The Deep Fix and The Black Corridor
• Megagesterine - Tokusou Sentai Dekaranger Episode 26: Cool Passion
• Mindflood - EVE Online
• Mongoose Blood - Alan Moore's Top 10 series - a very potent stimulant club drug that can make dancers move so fast they're rendered invisible.
• "The monkey drug" from Arrested Development (TV series)
• MUSCLE - Logan's Run
• Nalcon, Red - drugs that give psionic powers to the main protagonist in the Playstation game Galerians
• Nectar - Haze (video game) - Gives the user better speed, accuracy and strength; the ability to see enemies through cover by highlighting them and a hazard warning sense.
• Neotraxin - Six Million Dollar Man
• Nerve Sticks - EVE Online
• Noxosilinone aerodide - One Must Fall: 2097 (Mentioned in Raven's ending sequence)
• Orthopure Procreation Pills - The Running